HSG 2024: SPK-10001 GLP-tox Poster

SPK-10001 induces a durable and safe reduction of HTT protein supporting further development in Huntington’s disease Download FIle

HSG 2024: SPK-10001 ROA Poster

Route to a safe delivery strategy of AAV-based gene therapy to the caudate and putamen of nonhuman primates Download FIle

HSG 2024: SPK-10001 Pharmacology poster

SPK-10001 AAV-based microRNA mediates non-allele specific reduction of HTT mRNA through RNA interfernce, demonstrating its potential for further preclinical development. Download FIle

EAHAD 2024 – Durability in Mice Poster

EAHAD 2024 Poster:Analysis of Long-Term Expression Up To 72 Weeks of a Liver-Specific rAAV Gene Therapy Expressing the Human FVIII Transgene from Dirloctocogene Samoparvovec in Adult Mice Powered By EmbedPress

EAHAD 2024 – OSA Poster

EAHAD 2024 Poster:One Stage Assay Analysis Demonstrates that Gene Therapy-Derived Factor VIII (FVIII) from Dirloctocogene Samoparvovec Reduced Clot Times Compared to Endogenous FVIII at Comparable FVIII Levels Powered By EmbedPress